Volunteer Botanicals, conducted a gene expression study to determine how the company’s plant-based Satival powders would affect expression levels of 10 human genes closely associated with pain, wound healing and inflammation. Directed by Vanderbilt University Medical Center-trained Dr. Jacob H. Basham, the study concluded that the Satival plant-based powders demonstrated a significant increase in activation within these key genes.

This study shows without question that no longer is there just anecdotal reports of Satival powders generating a biological effect,” stated Derek Odette, chief executive officer at Volunteer Botanicals. “We now know that the cannabinoids, botanical and vitamin formulations using Satival powder initiates a measurable biological change in human genes.”

Conducted in June 2022, the study examined the changes in gene expression levels created in human cells when these cells were exposed to different Satival powders, formulated to aid with sleep, pain management or inflammation. The study was performed using the full thickness epiintestinal tissue model, a 3D reconstructed tissue model produced from normal, human-derived small intestinal epithelial cells, endothelial cells and fibroblasts. Each of the 10 genes studied are known to be utilized primarily by the immune system to regulate pain, inflammation and wound healing. Once exposed to the formulations, eight of the 10 genes observed had produced a statistically significant response within a 24-hour period.